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Eligibility: bfc5a7585cf323333fb99289fc9d6b8a [RDF]

Label bfc5a7585cf323333fb99289fc9d6b8a
Slug bfc5a7585cf323333fb99289fc9d6b8a
Criteria Inclusion Criteria: - Previously treated non-Hodgkin's lymphoma (all histologies except lymphoblastic and Burkitt's lymphoma) or Hodgkin's disease - Maximum of 4 previous treatment regimens - Measurable disease - No CNS involvement - Performance status - Zubrod 0-1 - Performance status - Karnofsky 80-100% - At least 12 weeks - Platelet count at least 75,000/mm^3 - Absolute neutrophil count greater than 1500/mm^3 - Lymphocyte count greater than 500/mm^3 - Hemoglobin at least 8.0 g/dL - Bilirubin less than 1.5 mg/dL - SGOT/SGPT less than 2 times normal - Creatinine no greater than 1.6 mg/dL - Creatinine clearance at least 60 mL/min - No severe cardiovascular disease including active ischemic heart disease, congestive heart failure, or major arrhythmias - No severe pulmonary disease including dyspnea with moderate to severe exertion - HIV negative - No active infection - Not pregnant or nursing - Fertile patients must use adequate contraception - No clinically significant autoimmune disease (e.g. rheumatoid arthritis) - No clinically significant gastrointestinal bleeding or uncontrolled peptic ulcer - No prior allogeneic bone marrow or stem cell transplant - At least 3 weeks since prior biologic therapy for lymphoma - At least 3 weeks since prior chemotherapy for lymphoma - No concurrent steroid therapy - At least 3 weeks since prior endocrine therapy for lymphoma - At least 3 weeks since prior radiotherapy for lymphoma - At least 2 weeks since prior surgery
Maximum age N/A
Healthy volunteers No
Study pop
Minimum age 16 Years
Gender Both
Sampling method
Similars None
Interlinks None